Correction: Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis

نویسندگان

  • Gianluca Bagnato
  • Alessandra Bitto
  • Natasha Irrera
  • Gabriele Pizzino
  • Donatella Sangari
  • Maurizio Cinquegrani
  • William Neal Roberts
  • Marco Atteritano
  • Domenica Altavilla
  • Francesco Squadrito
  • Gianfilippo Bagnato
  • Antonino Saitta
چکیده

* Correspondence: [email protected] Equal contributors Division of Internal Medicine, Department of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria n°1, 98100 Messina, Italy Figure 1 Immunostaining for α-SMA in cutaneous samples. Representative tissue sample from: (A) Sham animal; (B) HOCl mice; (C) HOCl + PTU animal (original magnification, ×40). The arrows show strong diffuse staining of myofibroblast nuclei (dark brown staining). (D) Number of myofibroblasts from the three experimental groups (HOCl + PTU group, n = 10; HOCl group, n = 10; Sham, n = 5). The increase of myofibroblast population in the skin of HOCl mice is prevented by propylthiouracil administration. Values are expressed as the mean and standard deviation. *P <0.001 versus Sham; #P <0.001 versus HOCl. α-SMA, alpha-smooth muscle actin; HOCl, hypochlorous acid; HPF, high-powered field; PTU, propylthiouracil.

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عنوان ژورنال:

دوره 16  شماره 

صفحات  -

تاریخ انتشار 2014